Testosterone down-regulates the levels of androgen receptor mRNA in smooth muscle cells from the rat corpora cavernosa via aromatization to estrogens
Estrogen has been shown to enhance myoelectric activity and tonic muscle tone in the genioglossus (2628), counteracting the reduction in cross-sectional area and proportion of type IIa fibers associated with estrogen deficiency and hypoxia, while also increasing the cross-sectional area of type IIb and IIx fibers (27)
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(2024) A review of therapies for hyperpigmentation modulating the synthesis of eumelanin to pheomelanin, Archives of Dermatological Research, [online]